ABOUT

Cell Fitness

Moreno Lab

Humans are able to detect fitness decay in colleagues by looking at the graying of the hair or the wrinkles in their faces. Work from my laboratory in the last few years has shown that cells can also detect fitness levels of neighboring cells using a molecular code. Those “fitness fingerprints” (Rhiner et al., Dev.Cell, 2010; Merino et al., Curr. Biol., 2013) can be used to mediate cell selection by recognizing and eliminating less fit cells during ageing (Merino et al., Cell, 2015), regeneration (Moreno et al., Curr. Biol., 2015) and cancer (Levayer et al., Nature 2015).

Info

Main Interests

The mechanisms by which cells of multicellular animals perform fitness detection and selection of neighbouring cells

Methods

Genetics, microscopy, live imaging

Models and Regions

Epithelial and neuronal tissue / Human cells, mouse and fruit fly

Opportunities

If you are interested in joining our group, please contact Eduardo Moreno at the email address bellow.

eduardo.moreno@research.fchampalimaud.org

Lab Webpage

moreno-lab.org

PROJECTS

Cell Fitness

Know our Projects

We are generally interested in how cells of multicellular animals can detect the fitness of neighboring cells selecting the fittest cells. This is a fundamental process that has implications in several broader fields, for example:

TEAM

Cell Fitness

Know our Team

Eduardo Moreno

Eduardo Moreno, PhD

Principal Investigator

Denise Camacho

Denise Camacho

External PhD Student

Catarina Costa

Catarina Costa

Masters Student

Pedro Durão

Pedro Durão

Masters Student

Maria Bettencourt

Maria Bettencourt

PhD Student

Ana Cristina Queirós

Ana Cristina Queirós, PhD

Postdoctoral Fellow

Catarina Brás Pereira

Catarina Brás Pereira, PhD

Postdoctoral Fellow

Dina Coelho

Dina Coelho, PhD

Postdoctoral Fellow

Andrea Spinazzola

Andrea Spinazzola

Student

Andrés Gutiérrez

Andrés Gutiérrez

Student

Irene Argudo

Irene Argudo

Student

Maria Carolina Rodrigues

Maria Carolina Rodrigues

Student

Mariana Reis

Mariana Reis

Student

Miguel Pinto

Miguel Pinto

Student

Joana Couceiro

Joana Couceiro

Technician

Esha Gogna

Esha Gogna, PhD

Visiting Scientist

Rajan Gogna

Rajan Gogna, PhD

Visiting Scientist

Telma Carrilho

Telma Carrilho

Lab Administrator

PUBLICATIONS

Know our Publications